Wheat: 200 Clinically Confirmed Reasons Not To Eat It

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Wheat: 200 Clinically Confirmed Reasons Not To Eat It

Sayer Ji

by Sayer Ji

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Wheat: 200 Clinically Confirmed Reasons Not To Eat It

With sales of foods labeled gluten free now reaching over 6 billion dollars a year, something truly profound is happening to the way in which Americans are perceiving the role of wheat in their diets. Once celebrated as the very poster-child of the health food movement, folks are increasingly rejecting this “king of grains,” and are now identifying it as being at the very root of their health problems.

Detractors claim that the movement is just a fad, or worse, that those who have embarked upon it without an official diagnosis are a bit crazy. After all, simply “feeling better” following gluten elimination is not considered to be proof of anything within the conventional medical system.  Biopsies, antibody, and genetic tests later, if nothing is found, and you still think gluten – this ‘sacred,’ omnipresent grain – is a problem, you might just get referred to a psychiatrist.

But anecdotes and “subjective experience” aside, the type of clinical research that constitutes “Truth,” with a capital T, from the perspective of the dominant medical establishment, can be found on the National Library of Medicine’s biomedical database known as MEDLINE. This vast bibliographic archive contains over 30 million citation entries, which as of time of this writing, contains 17,943 references to gluten. 

There has been a sharp increase in interest and research on the topic of “gluten intolerance” – although we prefer to label the subject “gluten toxicity,” in order to shift the focus away from the “victim” back to the “aggressor,” the gluten itself. In 1971, there were 71 studies listed on MEDLINE which referenced gluten. Last year in 2021, there were 1,130.  

One of our many interests here at GreenMedInfo.com is to identify “Problem Substances,” which is why we have created an index by that name with 698 subjects listed from A-Z.  If you navigate to WHEAT under the “W’s” you will find a list under “Advanced Topics” with 230 health conditions and/or adverse health effects associated with wheat consumption, all of which were determined solely through research in peer-reviewed and published medical journals indexed on MEDLINE.

You will also find, below the listed diseases, a “pharmacological actions” field set which lists 20 distinct ways in which wheat harms the body, e.g. nerve-damaging (neurotoxic), immune-damaging (immunoreactive), inflammatory, etc.

At present, the conventional medical establishment only identifies a handful of disorders likely to be caused by wheat consumption, such as:

  • Wheat Allergy
  • Celiac Disease
  • Dermatitis Herpetiformis
  • Exercise-Induced Wheat Anaphylaxis

These conditions, however, are but the tip of a massive “celiac” iceberg.  In a previous essay, The Dark Side of Wheat, we discussed the problem from a more philosophical perspective.  There is now, however, a huge dataset firmly establishing the likelihood that wheat intolerance, or better yet, wheat toxicity, is a universal, human species-specific problem, occurring only in differing degrees, and mostly sub-clinically, at least through the optic of conventional screenings and technologies.

One must also account for the “invisible thorn,” which is wheat lectin – known more technically as Wheat Germ Agglutinin (WGA) — and which can cause a broad range of adverse health effects, even while being undetected through conventional screenings.  Learn more about this topic in our essay Opening Pandora’s Bread Box: The Critical Role of Wheat Lectin in Human Disease.

In order to fully appreciate the extent of damage wheat and/or gluten consumption can have on the body, included “sprouted wheat” (since WGA is still present), view the screenshot from our Wheat page below:Quick Summary: 230 associated Diseases

    
NameCumulative KnowledgeArticle CountFocus Articles
Celiac Disease1395150focus
Wheat Intolerance40229focus
Gluten Sensitivity38035focus
Gluten Intolerance33627focus
Autoimmune Diseases13612focus
Schizophrenia1117focus
Food Allergies: Wheat10611focus
Food Allergies9710focus
Psoriasis825focus
Down Syndrome805focus
Diabetes Mellitus: Type 17312focus
Irritable Bowel Syndrome714focus
Diabetes Mellitus: Type 1: Prevention708focus
Celiac Disease: Diagnostic Considerations637focus
Autism Spectrum Disorders615focus
Sjogren’s Syndrome603focus
Cerebellar Ataxia534focus
Dermatitis Herpetiformis504focus
Epilepsy506focus
Graves Disease503focus
Liver Disease502focus
Multiple Myeloma503focus
Multiple Sclerosis503focus
Migraine Disorders445focus
Atopic Dermatitis404focus
Casein Intolerance402focus
Gastroesophageal Reflux402focus
Hyperthyroidism402focus
Anaphylaxis: Exercise-Induced375focus
IgA Nephropathy363focus
Gastrointestinal Inflammation345focus
Infertility312focus
Autoimmune Thyroiditis302focus
Cirrhosis: Liver301focus
Diarrhea: IBS associated301focus
Hypothyroidism303focus
IgA rheumatoid factor: elevated302focus
Infertility: Female301focus
Non-Hodgkin Lymphoma303focus
Polyarthritis301focus
Psychoses301focus
Eosinophilic esophagitis264focus
Epilepsy: With Cerebral Calcifications253focus
Cerebral Calcifications232focus
Diarrhea233focus
Celiac Disease: Prevention222focus
Abortion: Spontaneous212focus
Ataxia: Cerebellar213focus
Miscarriage: Recurrent212focus
Thyroid Nodule212focus
Atherosclerosis201focus
Attention Deficit Disorder with Hyperactivity202focus
Attention Deficit Hyperactivity Disorder201focus
Autism201focus
Cardiomyopathy201focus
Cholestasis201focus
Cholestasis: Autoimmune201focus
Coronary Artery Disease201focus
End-Stage Autoimmune Liver Disease (ESALD)201focus
Hashimoto’s thyroiditis201focus
IgE-Mediated Hypersensitivity202focus
Infant Nutrition201focus
Meniere’s Disease201focus
Organ Transplantation: Liver201focus
Palmoplantar Pustulosis201focus
Peripheral Neuropathies201focus
Restless Legs Syndrome202focus
Rett Syndrome201focus
Sensory Neuropathies201focus
Macroamylasemia194focus
Intestinal Permeability176focus
Asthma154focus
Ataxia143focus
Headache132focus
Pancreatitis132focus
Lymphoma122focus
Psychiatric Disorders122focus
Cancers: All112focus
Rheumatoid Arthritis112focus
Thyroid Cancer112focus
Acquired hypogammaglobulinemia101focus
Allergy: Cow’s Milk101focus
Anaphylaxis101focus
Aphthous Ulcer101focus
Ataxia: Dominant101focus
Ataxia: Sporadic101focus
Atopic Dermatitis: Infant & Childhood101focus
Attention Deficit Disorder101focus
Brain Injury: Hippocampal Damage101focus
CNS White Matter Abnormalities101focus
Carpal Tunnel Syndrome101focus
Celiac Disease: Early Onset101focus
Child Mortality101focus
Children: Impaired Growth101focus
Chronic Constipation, Children101focus
Colitis: Collagenous101focus
Constipation101focus
Depression: Unipolar101focus
Diarrhea: in Children101focus
Enamel Defects101focus
Epithelium Damage: Lymphocytic infiltration101focus
Food Allergies/Intolerances: Cereals/Grains101focus
Gastrointestinal Hemorrhage101focus
Gluten Ataxia101focus
Hepatitis: Autoimmune101focus
Hippocampal Sclerosis101focus
Hypertransaminasemia101focus
Hypogammaglobulinemia101focus
Kidney Cancer101focus
Liver Fibrosis101focus
Mania: Acute101focus
Microscopic Colitis Syndrome101focus
Mortality: All-Cause101focus
Mucosa: Flattened101focus
Myocarditis: Autoimmune101focus
Myopathies101focus
Myopathies: Inflammatory101focus
Nervous System Diseases101focus
Neurological Illness: GAD antibody-associated101focus
Nightshade Foods Intolerance101focus
Pregnancy: Prevention of Problems101focus
Small-for-gestational-age infant101focus
Spinocerebellar Ataxia Type 2101focus
Stiff-Person Syndrome101focus
Stomatitis: Aphthous101focus
Temporal Lobe Epilepsy (TLE)101focus
Thyroid Neoplasms101focus
Turner Syndrome101focus
Urinary Stone Disease101focus
Kidney Diseases92focus
Prolactin: Inappropriate Secretion82focus
Anemia72focus
Conjunctival Tumor61focus
Ectopic Calcification61focus
Encephalopathies61focus
Glomerulonephritis61focus
Hypocalcemia61focus
Neuromyelitis Optica62focus
Pituitary Diseases61focus
Polyneuropathies61focus
Prolactin Hypersecretion Syndrome62focus
Seizures61focus
Splenic Calcifications61focus
Splenic Diseases61focus
Systemic Lupus Erythematosus61focus
Urticaria62focus
Immune Disorders: Low Immune Function51focus
Malabsorption Syndrome52focus
Enteropathy42focus
Insulin: Elevated42focus
Male Hormone Imbalances41focus
Diabetes Mellitus: Type 231focus
Facial Palsy31focus
Folic Acid/Folate Deficiency31focus
Food Allergy: Immunoglobulin E-mediated31focus
Gastrointestinal Diseases32focus
Hydronephrosis31focus
Hyperamylasemia31focus
Inflammation32focus
Insulin Disorders32focus
Kidney Stones31focus
Opiate Addiction/Withdrawal31focus
Osteogenesis Imperfecta31focus
Osteomalacia31focus
Osteopenia31focus
Osteoporosis31focus
Parathyroid Diseases31focus
Parathyroid adenoma31focus
Stroke31focus
Thrombosis31focus
Tremor31focus
Urolithiasis31focus
Uveitis31focus
A1C21focus
Allergies21focus
Blood-Brain-Barrier Disorders22focus
Demyelinating Diseases21focus
Diabetes: Glycation/A1C21focus
Drug Toxicity: Methotrexate21focus
Glucagon: Excess Secretion21focus
Gynecomastia21focus
HPA Axis Dysregulation21focus
Insulinitis21focus
Low Immune Function: Thymus Dysfunction21focus
Serotonin Disorders21focus
Thymus Atrophy21focus
Ataxia: Idiopathic11focus
Brain: Microglial Activation11focus
Breast Cancer11focus
Chorea11focus
Clotting11focus
Dementia11focus
Food Poisoning11focus
Guillain-Barre Syndrome11focus
Huntington Disease11focus
Hyperinsulinism11focus
Insulin Resistance11focus
Lane-Hamilton syndrome11focus
Lectin-Induced Toxicity11focus
Miscarriage11focus
Myelopathy11focus
Neurologic Disorders11focus
Neuropathy11focus
Osteoarthritis11focus
Oxidative Stress11focus

Quick Summary: 22 associated Adverse Pharmacological Actions

    
NameCumulative KnowledgeArticle CountFocus Articles
Neurotoxic28723focus
Immunoreactive12813focus
Immunotoxic999focus
Teratogenic914focus
Inflammatory406focus
Interleukin-15 downregulation222focus
Proliferative201focus
Nephrotoxic132focus
Diabetogenic124focus
Allergenic112focus
Cardiotoxic101focus
Endocrine Disruptor62focus
Immunosuppressive51focus
Cytotoxic44focus
Endocrine Disruptor: Insulin Resistance21focus
Endocrine Disruptor: Pancreas21focus
Serotonin Down-Regulation21focus
Interleukin-4 Up-Regulation11focus
Oxidant11focus
Vascular Endothelial Growth Factor C Up-Regulation11focus

Related Databases

Diseases

Oxidative Stress6,687Inflammation6,097Diabetes Mellitus: Type 23,330Breast Cancer3,248Cancers: All2,268Osteoporosis1,723Asthma1,612Atherosclerosis1,543Multiple Sclerosis1,238Insulin Resistance1,169Osteoarthritis715Atopic Dermatitis679Psoriasis665Autism Spectrum Disorders648Rheumatoid Arthritis632Diabetes Mellitus: Type 1555Schizophrenia479Liver Fibrosis465Dementia403Epilepsy402Irritable Bowel Syndrome392Autoimmune Diseases374Stroke372Thyroid Cancer324Multiple Myeloma304Celiac Disease299Hypothyroidism295Constipation284Coronary Artery Disease282Infertility: Female234Allergies222Pancreatitis216Food Allergies211Diarrhea199Cardiomyopathy198Kidney Cancer198Huntington Disease187Lymphoma177Gastrointestinal Inflammation172Seizures170Autism168Brain: Microglial Activation143Thrombosis130Liver Disease121Immune Disorders: Low Immune Function118Systemic Lupus Erythematosus114Drug Toxicity: Methotrexate113Kidney Stones105Uveitis104Attention Deficit Disorder with Hyperactivity100Gluten Sensitivity99Psychiatric Disorders97Graves Disease95Headache93Infertility88Kidney Diseases81Gastrointestinal Diseases78Carpal Tunnel Syndrome76IgA Nephropathy76Peripheral Neuropathies76Urticaria75Attention Deficit Hyperactivity Disorder71Hyperinsulinism68Abortion: Spontaneous66Migraine Disorders65Mortality: All-Cause63Osteopenia63Gastroesophageal Reflux62Sjogren’s Syndrome60Allergy: Cow’s Milk58Anemia56Hyperthyroidism56Cholestasis55Myopathies54Demyelinating Diseases50Restless Legs Syndrome49Miscarriage47Neurologic Disorders46Intestinal Permeability45Guillain-Barre Syndrome43Anaphylaxis41Folic Acid/Folate Deficiency41Aphthous Ulcer38Autoimmune Thyroiditis37Non-Hodgkin Lymphoma36Clotting34Stomatitis: Aphthous34Diabetes: Glycation/A1C33Organ Transplantation: Liver32Hepatitis: Autoimmune30Down Syndrome28Diarrhea: in Children27Psychoses27IgE-Mediated Hypersensitivity26Urolithiasis25Atopic Dermatitis: Infant & Childhood21Brain Injury: Hippocampal Damage21Serotonin Disorders20Attention Deficit Disorder19Blood-Brain-Barrier Disorders18Glomerulonephritis17Malabsorption Syndrome15Myocarditis: Autoimmune15Celiac Disease: Diagnostic Considerations14Ectopic Calcification14Food Allergies: Wheat14HPA Axis Dysregulation14Infant Nutrition14Thyroid Nodule14Diarrhea: IBS associated13Gynecomastia13Insulin: Elevated13Child Mortality11Neuromyelitis Optica11Enteropathy10Insulin Disorders10A1C8Eosinophilic esophagitis8Food Poisoning8Mania: Acute8Miscarriage: Recurrent8Tremor8Anaphylaxis: Exercise-Induced7Ataxia7Ataxia: Cerebellar7Casein Intolerance7Encephalopathies7Polyneuropathies7Cirrhosis: Liver6Gastrointestinal Hemorrhage6Osteomalacia6Rett Syndrome6Small-for-gestational-age infant6Celiac Disease: Prevention5Cerebellar Ataxia5Dermatitis Herpetiformis5Low Immune Function: Thymus Dysfunction5Meniere’s Disease5Polyarthritis5Pregnancy: Prevention of Problems5Children: Impaired Growth4Epilepsy: With Cerebral Calcifications4Lectin-Induced Toxicity4Macroamylasemia4Acquired hypogammaglobulinemia3Cerebral Calcifications3Gluten Ataxia3Hypocalcemia3Male Hormone Imbalances3Myelopathy3Parathyroid Diseases3Splenic Diseases3Ataxia: Idiopathic2Food Allergy: Immunoglobulin E-mediated2Hydronephrosis2Hypertransaminasemia2IgA rheumatoid factor: elevated2Lane-Hamilton syndrome2Myopathies: Inflammatory2Nervous System Diseases2Neuropathy2Pituitary Diseases2Prolactin Hypersecretion Syndrome2Prolactin: Inappropriate Secretion2Spinocerebellar Ataxia Type 22Temporal Lobe Epilepsy (TLE)2Thyroid Neoplasms2Ataxia: Dominant1Ataxia: Sporadic1CNS White Matter Abnormalities1Celiac Disease: Early Onset1Cholestasis: Autoimmune1Chorea1Chronic Constipation, Children1Colitis: Collagenous1Conjunctival Tumor1Enamel Defects1End-Stage Autoimmune Liver Disease (ESALD)1Facial Palsy1Glucagon: Excess Secretion1Hippocampal Sclerosis1Hyperamylasemia1Hypogammaglobulinemia1Insulinitis1Microscopic Colitis Syndrome1Mucosa: Flattened1Neurological Illness: GAD antibody-associated1Nightshade Foods Intolerance1Osteogenesis Imperfecta1Palmoplantar Pustulosis1Parathyroid adenoma1Sensory Neuropathies1Splenic Calcifications1Stiff-Person Syndrome1Thymus Atrophy1Turner Syndrome1Urinary Stone Disease1

Pharmacological Actions

Cytotoxic246Proliferative113Interleukin-15 downregulation3

Adverse Pharmacological Actions

Neurotoxic763Cardiotoxic249Oxidant249Inflammatory187Immunotoxic136Cytotoxic125Endocrine Disruptor106Teratogenic70Immunoreactive65Diabetogenic58Immunosuppressive56Nephrotoxic52Endocrine Disruptor: Insulin Resistance37Proliferative14Allergenic6Endocrine Disruptor: Pancreas2Interleukin-15 downregulation2Serotonin Down-Regulation2Vascular Endothelial Growth Factor C Up-Regulation2Interleukin-4 Up-Regulation1

Problem Substances

Wheat111Wheat Germ Agglutinin (WGA)41

Sayer Ji

Sayer Ji

Sayer Ji is founder of Greenmedinfo.com, author of international best-seller REGENERATE: Unlocking Your Body’s Radical Resilience through the New Biology, co-founder of Stand for Health Freedom (501c4), and UNITE.live, a global, multi-media platform for conscious creators and their communities. 

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